Src I338G-IN-3g |CAS:206991-94-8 Probechem Biochemicals

Chemical Structure : Src I338G-IN-3g

Src I338G-IN-3g (Src I338G inhibitor 3g)

Catalog No.: PC-70245Not For Human Use, Lab Use Only.

A potent, selective, cell-permeable I338G v-Src inhibitor with IC50 of 430 nM, shows no inhibition of wild-type v-Src at 300 uM.

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Biological Activity

Src I338G-IN-3g is a potent, selective, cell-permeable I338G v-Src inhibitor with IC50 of 430 nM, shows no inhibition of wild-type v-Src at 300 uM.
Src I338G-IN-3g inhibits p36 phosphotyrosine signal in cells expressing I338G v-Src with IC50 of 50 uM.

Physicochemical Properties

M.Wt	427.552
Formula	C26H29N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(tert-butyl)-N-(1-(tert-butyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)benzamide

References

1. Bishop AC, et al. Curr Biol. 1998 Feb 26;8(5):257-66.

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Src I338G-IN-3g (Src I338G inhibitor 3g)

Biological Activity

Physicochemical Properties

References

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