Src inhibitor PP2 | Src inhibitor | Probechem Biochemicals

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Chemical Structure : Src inhibitor PP2

CAS No.: 172889-27-9

Src inhibitor PP2 (Src family tyrosine kinases inhibitor)

Catalog No.: PC-24573Not For Human Use, Lab Use Only.

PP2 is a potent, reversible and ATP-competitive Src family kinases inhibitor with IC50 of 4 and 5 nM for Lck and Fyn, respectively, also inhibits RIPK3 with IC50 of 29 nM.

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5 mg	$48	In stock
10 mg	$78	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PP2 is a potent, reversible and ATP-competitive Src family kinases inhibitor with IC50 of 4 and 5 nM for Lck and Fyn, respectively, also inhibits RIPK3 with IC50 of 29 nM.

Physicochemical Properties

M.Wt	301.78
Formula	C15H16ClN5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(tert-Butyl)-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

References

1. Nagao M, et al. J Biol Chem. 1998 Sep 4;273(36):22892-8.

2. Taylor VC, et al. J Biol Chem. 1999 Apr 23;274(17):11505-12.

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Src inhibitor PP2 (Src family tyrosine kinases inhibitor)

Biological Activity

Physicochemical Properties

References

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