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Stafib-1

Chemical Structure : Stafib-1

CAS No.: 1688703-26-5

Stafib-1 (Stafib 1)

Catalog No.: PC-61166Not For Human Use, Lab Use Only.

Stafib-1 is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 44 nM, >50-fold selectivity over STAT5a.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Stafib-1 is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 44 nM, >50-fold selectivity over STAT5a.

Physicochemical Properties

M.Wt 602.429
Formula C26H24N2O11P2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((2-((6-(phenylcarbamoyl)naphthalen-2-yl)oxy)acetamido)methyl)-1,2-phenylene bis(dihydrogen phosphate)

References

1. Elumalai N, et al. Angew Chem Int Ed Engl. 2015 Apr 13;54(16):4758-63.

2. Elumalai N, et al. Sci Rep. 2017 Apr 11;7(1):819.

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