Stafori-2 | STAT4 inhibitor | Probechem Biochemicals

Chemical Structure : Stafori-2

Stafori-2 (Stafori 2)

Catalog No.: PC-25480Not For Human Use, Lab Use Only.

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Biological Activity

Stafori-2 is the phosphate analog of Stafori-1 and potent, selective small molecule inhibitor of STAT4 Src homology 2 domain with Ki of 0.18 uM in FP assays, shows good selectivity over other STAT family members.
Stafori-2 binds to STAT4 with ITC Kd of 3.1 uM.
Stafori-2 is twofold more potent than the corresponding phosphonate Stafori-1 (Kd=7.1 uM).

Physicochemical Properties

M.Wt	288.23
Formula	C11H10FO4PS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-fluoro-4-(5-methylthiophen-3-yl)phenyl dihydrogen phosphate

References

1. Brovchenko N, et al. ChemMedChem. 2025 Sep 9:e202500672.

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Stafori-2 (Stafori 2)

Biological Activity

Physicochemical Properties

References

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