Stromatoxin-1 (Stromatoxin 1, ScTx1)

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Chemical Structure : Stromatoxin-1

Catalog No.: PC-28231Not For Human Use, Lab Use Only.

Stromatoxin-1 (Stromatoxin 1, ScTx1) is a peptide isolated from tarantulas and specific inhibitor of Kv2 channels, inhibits Kv2.1, Kv2.2, Kv4.2, and Kv2.1/9.3 channels.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Stromatoxin-1 (Stromatoxin 1, ScTx1) is a peptide isolated from tarantulas and specific inhibitor of Kv2 channels, inhibits Kv2.1, Kv2.2, Kv4.2, and Kv2.1/9.3 channels.

Physicochemical Properties

M.Wt	3791.31
Formula	C156H237N49O48S7
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Asp-Cys-Thr-Arg-Met-Phe-Gly-Ala-Cys-Arg-Arg-Asp-Ser-Asp-Cys-Cys-Pro-His-Leu-Gly-Cys-Lys-Pro-Thr-Ser-Lys-Tyr-Cys-Ala-Trp-Asp-Gly-Thr-Ile-NH2 (Disulfide bridge: Cys2-Cys16, Cys9-Cys21, Cys15-Cys28)

References

1. Shiau YS, et al. Chem Res Toxicol. 2003 Oct;16(10):1217-25.

2. Amberg GC, et al. Am J Physiol Cell Physiol. 2006 Aug;291(2):C348-56.

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