Catalog No.: PC-62421Not For Human Use, Lab Use Only.
Sudemycin E is an alternative splicing inhibitor that binds to the U2 small nuclear ribonucleoprotein (snRNP) component SF3B1, causes a rapid change in alternative pre-messenger RNA splicing.
Sudemycin E is an alternative splicing inhibitor that binds to the U2 small nuclear ribonucleoprotein (snRNP) component SF3B1, causes a rapid change in alternative pre-messenger RNA splicing.
Sudemycin E changes overall gene expression and arrest in the G2 phase of the cell cycle, and causes a loss of the H3K36me3 modification in chromatin encoding these exons.
Sudemycin E induces changes in chromatin modifications that result in chromatin condensation.
