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Chemical Structure : Sudemycin K
Catalog No.: PC-62422Not For Human Use, Lab Use Only.
Sudemycin K is a synthetic antitumor splicing inhibitor with IC50 of 15 nM (MCL1 alternative splicing regulation), shows cytotoxicity in HeLa cells with IC50 of 2.3 nM.
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Sudemycin K is a synthetic antitumor splicing inhibitor with IC50 of 15 nM (MCL1 alternative splicing regulation), shows cytotoxicity in HeLa cells with IC50 of 2.3 nM.
Sudemycin K has an IC50 of 250 nM in vitro spliceosome (A3’ complex) formation assays.
| M.Wt | 486.697 | |
| Formula | C29H46N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Makowski K, et al. ACS Chem Biol. 2017 Jan 20;12(1):163-173.
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