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Sulconazole mononitrate

Chemical Structure : Sulconazole mononitrate

CAS No.: 61318-91-0

Sulconazole mononitrate ((±)-Sulconazole mononitrate)

Catalog No.: PC-27945Not For Human Use, Lab Use Only.

Sulconazole mononitrate is an imidazole derivative broad-spectrum fungicide with activity against dermatophytes and yeasts, and some gram-positive bacteria, including Staphylococcus aureus, S epidermidis, and Streptococcus faecalis, inhibits the enzyme 14 demethylase, impairing the biosynthesis of ergosterol, which is essential for fungal cell wall synthesis.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Sulconazole mononitrate is an imidazole derivative broad-spectrum fungicide with activity against dermatophytes and yeasts, and some gram-positive bacteria, including Staphylococcus aureus, S epidermidis, and Streptococcus faecalis, inhibits the enzyme 14 demethylase, impairing the biosynthesis of ergosterol, which is essential for fungal cell wall synthesis.

Physicochemical Properties

M.Wt 460.75
Formula C18H16Cl3N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate

References

1. Fass M, et al. J Pharm Sci. 1981 Dec;70(12):1338-40.

2. Beggs WH. J Antimicrob Chemother. 1985 Sep;16(3):397-9.

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