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Chemical Structure : Suplatast tosilate
CAS No.: 94055-76-2
Catalog No.: PC-45128Not For Human Use, Lab Use Only.
A Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production.
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A Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production; suppresses IgE production, eosinophil infiltration and histamine release; exhibits antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active.
Allergy
Approved
| M.Wt | 499.6406 | |
| Formula | C23H33NO7S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 33 mg/mL |
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| Chemical Name/SMILES |
Sulfonium, [3-[[4-(3-ethoxy-2-hydroxypropoxy)phenyl]amino]-3-oxopropyl]dimethyl-, 4-methylbenzenesulfonate (1:1) |
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1. Taniguchi H, et al. Eur J Pharmacol. 1996 Dec 30;318(2-3):447-54.
2. Konno S, et al. Eur J Pharmacol. 1994 Jun 23;259(1):15-20.
3. Furonaka M, et al. J Pharmacol Exp Ther. 2009 Jan;328(1):55-61.
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