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Suplatast tosilate

Chemical Structure : Suplatast tosilate

CAS No.: 94055-76-2

Suplatast tosilate (IPD-1151T, IPD1151T)

Catalog No.: PC-45128Not For Human Use, Lab Use Only.

Suplatast tosilate (IPD-1151T) is a Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production.

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Biological Activity

Suplatast tosilate (IPD-1151T) is a Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production.
Suplatast tosilate suppresses IgE production, eosinophil infiltration and histamine release.
Suplatast tosilate exhibits antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active.

Physicochemical Properties

M.Wt 499.6406
Formula C23H33NO7S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 33 mg/mL

Chemical Name/SMILES

Sulfonium, [3-[[4-(3-ethoxy-2-hydroxypropoxy)phenyl]amino]-3-oxopropyl]dimethyl-, 4-methylbenzenesulfonate (1:1)

References

1. Taniguchi H, et al. Eur J Pharmacol. 1996 Dec 30;318(2-3):447-54.

2. Konno S, et al. Eur J Pharmacol. 1994 Jun 23;259(1):15-20.

3. Furonaka M, et al. J Pharmacol Exp Ther. 2009 Jan;328(1):55-61.

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