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Sutezolid

Chemical Structure : Sutezolid

CAS No.: 168828-58-8

Sutezolid (PNU-100480, PNU100480, PF-02341272, U-100480)

Catalog No.: PC-42559Not For Human Use, Lab Use Only.

Sutezolid (PNU-100480, PF-02341272) is an oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo, by inhibiting bacterial protein synthesis.

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Biological Activity

Sutezolid (PNU-100480, PF-02341272) is an oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo, by inhibiting bacterial protein synthesis.
Sutezolid significantly shorten the duration of therapy for drug-susceptible as well as multidrug-resistant tuberculosis.

Physicochemical Properties

M.Wt 353.4117
Formula C16H20FN3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-

References

1. Cynamon MH, et al. Antimicrob Agents Chemother. 1999 May;43(5):1189-91.

2. Williams KN, et al. Antimicrob Agents Chemother. 2009 Apr;53(4):1314-9.

3. Williams KN, et al. Am J Respir Crit Care Med. 2009 Aug 15;180(4):371-6.

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