Chemical Structure : Synaptamide
CAS No.:
162758-94-3
Synaptamide
(Docosahexaenoyl ethanolamide)
Catalog No. : PC-42077Not For Human Use, Lab Use Only.
An endogenous DHA metabolite that promotes neurite growth, synaptogenesis, and synaptic function both in vitro and in vivo.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4207701
Biological Activity
An endogenous DHA metabolite that promotes neurite growth, synaptogenesis, and synaptic function both in vitro and in vivo; significantly increased the number of MAP2 and Tuj-1-positive neurons with concomitant induction of PKA/CREB phosphorylation at low nM; induces neuronal differentiation of NSCs.
Physicochemical Properties
M.Wt
371.5561
Formula
C24H37NO2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO; Ethanol: 25 mg/mL
Chemical Name/SMILES
4,7,10,13,16,19-Docosahexaenamide, N-(2-hydroxyethyl)-, (4Z,7Z,10Z,13Z,16Z,19Z)-
References
1. Rashid MA, et al. J Neurochem. 2013 Jun;125(6):869-84.
2. Kim HY, et al. Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):114-20.
3. Rashid MA, et al. Neuropharmacology. 2016 Mar;102:174-85.
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