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Syrosingopine

Chemical Structure : Syrosingopine

CAS No.: 84-36-6

Syrosingopine (Su 3118)

Catalog No.: PC-26718Not For Human Use, Lab Use Only.

Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, reduces glycolysis and induces synthetic lethality in cancer cells when combine with metformin.

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Biological Activity

Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, reduces glycolysis and induces synthetic lethality in cancer cells when combine with metformin.

Physicochemical Properties

M.Wt 666.72
Formula C35H42N2O11
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methyl (1S,2R,3R,4aS,13bR,14aS)-3-((4-((ethoxycarbonyl)oxy)-3,5-dimethoxybenzoyl)oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate

References

1. Benjamin D, et al. Cell Rep. 2018 Dec 11;25(11):3047-3058.e4.

2. Lefèvre-Borg F, et al. Hypertension. 1988 Apr;11(4):360-70.

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