T-10430 | BLT2 agonist | Probechem Biochemicals

Chemical Structure : T-10430

T-10430 (T10430)

Catalog No.: PC-23851Not For Human Use, Lab Use Only.

T-10430 is a potent and selective agonist of leukotriene B4 receptor 2 (BLT2) with EC50 of 0.51 nM in cAMP assays.

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Biological Activity

T-10430 is a potent and selective agonist of leukotriene B4 receptor 2 (BLT2) with EC50 of 0.51 nM in cAMP assays.
T-10430 displays broad selectivity within a broad range of GPCRs, including related receptors BLT1 and AT1.
T-10430 is a chemical probe to study the consequences of BLT2 activation in vitro and in vivo.

Physicochemical Properties

M.Wt	326.40
Formula	C17H22N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(6-(2-(1H-Tetrazol-5-yl)phenyl)-2,6-diazaspiro[3.3]heptan-2-yl)pentan-1-one

References

1. Hernandez-Olmos V, et al. J Med Chem. 2025 Jan 13. doi: 10.1021/acs.jmedchem.4c01617.

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T-10430 (T10430)

Biological Activity

Physicochemical Properties

References

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