Catalog No.: PC-62057Not For Human Use, Lab Use Only.
T-1105 is a broad-spectrum antiviral inhibitor that demonstrates good activity for various RNA viruses, including influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV), FMDV, and ZIKV.
T-1105 is a broad-spectrum antiviral inhibitor that demonstrates good activity for various RNA viruses, including influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV), FMDV, and ZIKV.
T-1105 inhibits ZIKV replication with EC50 of 35 uM in a virus yield reduction assay.
Physicochemical Properties
M.Wt
139.114
Formula
C5H5N3O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Pyrazinecarboxamide, 3,4-dihydro-3-oxo- (9CI)
References
1. Furuta Y, et al. Antiviral Res. 2009 Jun;82(3):95-102.
2. Zmurko J, et al. PLoS Negl Trop Dis. 2016 May 10;10(5):e0004695.
3. Naesens L, et al. Mol Pharmacol. 2013 Oct;84(4):615-29.
