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T-box-i

Chemical Structure : T-box-i

CAS No.: 2728061-30-9

T-box-i (T-box riboswitch inhibitor)

Catalog No.: PC-25555Not For Human Use, Lab Use Only.

T-box-I is a specific small molecule inhibitor of transcriptional T-box riboswitches, efficiently disrupts T-box riboswitch-mediated transcription, inhibits S. aureus growth and does not induce antibiotic resistance.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

T-box-I is a specific small molecule inhibitor of transcriptional T-box riboswitches, efficiently disrupts T-box riboswitch-mediated transcription, inhibits S. aureus growth and does not induce antibiotic resistance.

Physicochemical Properties

M.Wt 408.26
Formula C18H14BrN7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(5-(3-bromophenyl)-1H-imidazol-2-yl)-3,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazin-2-amine

References

1. Giarimoglou N, et al. RNA. 2025 Sep 17:rna.080644.125.

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