T338C Src-IN-2 |CAS:1351927-00-8 Probechem Biochemicals

Chemical Structure : T338C Src-IN-2

T338C Src-IN-2

Catalog No.: PC-45085Not For Human Use, Lab Use Only.

T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM, also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM.

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Biological Activity

T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM, also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM.

Physicochemical Properties

M.Wt	327.3561
Formula	C17H18FN5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethanone, 1-[3-[[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]methyl]phenyl]-2-fluoro-

References

1. Garske AL, et al. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52.

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T338C Src-IN-2

Biological Activity

Physicochemical Properties

References

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