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Chemical Structure : T5910047
Catalog No.: PC-35815Not For Human Use, Lab Use Only.
T5910047 (T-5910047) is a small molecule inhibitor of MyD88-dependent signaling pathways, disrupts MyD88 homodimeric formation.
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T5910047 (T-5910047) is a small molecule inhibitor of MyD88-dependent signaling pathways, disrupts MyD88 homodimeric formation.
T5910047 inhibits SEB-induced inhibition of cytokine production in PBMCs with IC50 of 2-10 uM.
T5910047 also inhibits SEA-induced pro-inflammatory cytokine production, shows no toxicity in primary cells up to 100 uM.
| M.Wt | 436.589 | |
| Formula | C20H28N4O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Olson MA, et al. Sci Rep. 2015 Sep 18;5:14246.
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