Chemical Structure : TA-02
CAS No.: 1784751-19-4
Catalog No.: PC-42059Not For Human Use, Lab Use Only.
TA-02 is a potent p38 MAPK inhibitor with IC50 of 20 nM.
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TA-02 is a potent p38 MAPK inhibitor with IC50 of 20 nM.
TA-02 inhibits the phosphorylation of proteins downstream of p38α MAPK such as MAPKAPK2 and HSP27 during cardiogenesis, and increases ATF-2 and MEF2C during cardiac differentiation.
M.Wt | 333.3341 | |
Formula | C20H13F2N3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Pyridine, 4-[2-(2-fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]- |
1. Laco F, et al. J Mol Cell Cardiol. 2015 Mar;80:56-70.
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