TA-1887 | SGLT2 inhibitor | Probechem Biochemicals

Chemical Structure : TA-1887

TA-1887 (JNJ-39933673, TA1887)

Catalog No.: PC-63415Not For Human Use, Lab Use Only.

TA-1887 (JNJ-39933673) is a potent, selective SGLT2 inhibitor with IC50 of 1.4 nM, is a novel antihyperglycemic agents through inhibition of renal SGLT2.

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Biological Activity

TA-1887 (JNJ-39933673) is a potent, selective SGLT2 inhibitor with IC50 of 1.4 nM, is a novel antihyperglycemic agents through inhibition of renal SGLT2.

Physicochemical Properties

M.Wt	427.47
Formula	C24H26FNO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3R,4S,5S,6R)-2-(3-(4-cyclopropylbenzyl)-4-fluoro-1H-indol-1-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

References

1. Wang XX, et al. J Biol Chem. 2017 Mar 31;292(13):5335-5348.

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TA-1887 (JNJ-39933673, TA1887)

Biological Activity

Physicochemical Properties

References

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