TAK-456 | Antifungal | Probechem Biochemicals

Chemical Structure : TAK-456

TAK-456 (TAK456)

Catalog No.: PC-27773Not For Human Use, Lab Use Only.

TAK-456 is an oral triazole with potent and broad-spectrum in vitro antifungal activity shows MIC90 of 0.25 ug/mL against clinical isolates of Candida spp., Aspergillus spp., and Cryptococcus neoformans, except for Candida glabrata.

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Biological Activity

Physicochemical Properties

M.Wt	481.47
Formula	C22H21F2N9O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(1H-tetrazol-1-yl)phenyl)-3-((2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)imidazolidin-2-one

References

1. Tsuchimori N, et al. Antimicrob Agents Chemother. 2002 May;46(5):1388-93.

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TAK-456 (TAK456)

Biological Activity

Physicochemical Properties

References

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