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TAK-615

Chemical Structure : TAK-615

CAS No.: 1664335-55-0

TAK-615 (TAK615)

Catalog No.: PC-35273Not For Human Use, Lab Use Only.

TAK-615 (TAK615) is a potent, selective, negative allosteric modulator (NAM) of the LPA1 receptor, partially inhibits the LPA response with IC50 of 91 nM (60% at 10 uM) in calcium mobilisation assays..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TAK-615 (TAK615) is a potent, selective, negative allosteric modulator (NAM) of the LPA1 receptor, partially inhibits the LPA response with IC50 of 91 nM (60% at 10 uM) in calcium mobilisation assays.

Physicochemical Properties

M.Wt 419.452
Formula C25H22FNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((N-(cyclopropylmethyl)-4-(2-fluorophenoxy)benzamido)methyl)benzoic acid

References

1. Ellery J, et al. Eur J Pharmacol. 2018 May 26;833:8-15.

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