TAK1-IN-1 |CAS:1356013-39-2 Probechem Biochemicals

Chemical Structure : TAK1-IN-1

TAK1-IN-1

Catalog No.: PC-62810Not For Human Use, Lab Use Only.

TAK1-IN-1 is a potent, selective, Type I (ATP-competitive, DFG-in) TAK1 inhibitor with Kd of 59 nM, a thienopyrimidine scaffold that serves as a good starting point for medicinal chemistry..

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Biological Activity

TAK1-IN-1 is a potent, selective, Type I (ATP-competitive, DFG-in) TAK1 inhibitor with Kd of 59 nM, a thienopyrimidine scaffold that serves as a good starting point for medicinal chemistry.

Physicochemical Properties

M.Wt	336.369
Formula	C17H12N4O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(7-methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide

References

1. Miura T, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1031-1036.

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TAK1-IN-1

Biological Activity

Physicochemical Properties

References

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