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Chemical Structure : TAM-16
CAS No.: 2030241-59-7
Catalog No.: PC-60356Not For Human Use, Lab Use Only.
TAM-16 is a benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13 with IC50 of 0.32 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $148 | In stock | |
| 10 mg | $228 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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TAM-16 is a benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13 with IC50 of 0.32 uM.
TAM-16 show highly potent in vitro bactericidal activity against drug-susceptible and drug-resistant clinical isolates of M. tuberculosis (MICs: 0.06-0.25 uM).
TAM-16 exhibits in vivo efficacy in multiple mouse models of TB infection, has excellent pharmacological and safety profiles.
| M.Wt | 380.444 | |
| Formula | C22H24N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
5-hydroxy-2-(4-hydroxyphenyl)-N-methyl-4-(piperidin-1-ylmethyl)-2,3-dihydrobenzofuran-3-carboxamide |
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1. Aggarwal A, et al. Cell. 2017 Jul 13;170(2):249-259.e25.
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