TAM-IN-1 |CAS:1454847-05-2 Probechem Biochemicals

Chemical Structure : TAM-IN-1

Catalog No.: PC-61780Not For Human Use, Lab Use Only.

TAM-IN-1 is a highly potent, macrocyclic inhibitor of Mer and Axl with Ki of <50 pM and 130 pM, respectively..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TAM-IN-1 is a highly potent, macrocyclic inhibitor of Mer and Axl with Ki of <50 pM and 130 pM, respectively.

M.Wt	460.894
Formula	C21H22ClFN6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-25-amino-56-chloro-55-fluoro-11-(2-hydroxyethyl)-13,4,7-trimethyl-11H-3-oxa-7-aza-2(2,6)-pyrazina-1(4,5)-pyrazola-5(1,2)-benzenacyclooctaphan-6-one

1. Gajiwala KS, et al. J Biol Chem. 2017 Sep 22;292(38):15705-15716.