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Chemical Structure : TAS-301
CAS No.: 193620-69-8
Catalog No.: PC-45578Not For Human Use, Lab Use Only.
TAS-301 is an inhibitor of smooth muscle cell migration and proliferation, inhibits PDGF-induced tyrosine phosphorylation of both FAK and paxillin.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | Get quote |
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TAS-301 is an inhibitor of smooth muscle cell migration and proliferation, inhibits PDGF-induced tyrosine phosphorylation of both FAK and paxillin.
TAS-301 also inhibits PDGF-induced elevation of [Ca2+]i and activation of CaMK II, reduces the extent of F-actin stress fiber depolymerization observed in response to PDGF at 10 uM.
| M.Wt | 357.4019 | |
| Formula | C23H19NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 38 mg/mL |
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| Chemical Name/SMILES |
2H-Indol-2-one, 3-[bis(4-methoxyphenyl)methylene]-1,3-dihydro- |
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1. Sasaki E, et al. J Pharmacol Exp Ther. 2000 Dec;295(3):1043-50.
2. Muranaka Y, et al. J Pharmacol Exp Ther. 1998 Jun;285(3):1280-6.
3. Sasaki E, et al. Pharmacology. 2001 Jul;63(1):17-27.
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