Chemical Structure : TAS-301
CAS No.:
193620-69-8
TAS-301
(TAS301)
Catalog No. : PC-45578Not For Human Use, Lab Use Only.
TAS-301 is an inhibitor of smooth muscle cell migration and proliferation, inhibits PDGF-induced tyrosine phosphorylation of both FAK and paxillin.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4557801
Biological Activity
TAS-301 is an inhibitor of smooth muscle cell migration and proliferation, inhibits PDGF-induced tyrosine phosphorylation of both FAK and paxillin.
Physicochemical Properties
M.Wt
357.4019
Formula
C23H19NO3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 38 mg/mL
Chemical Name/SMILES
2H-Indol-2-one, 3-[bis(4-methoxyphenyl)methylene]-1,3-dihydro-
References
1. Sasaki E, et al. J Pharmacol Exp Ther. 2000 Dec;295(3):1043-50.
2. Muranaka Y, et al. J Pharmacol Exp Ther. 1998 Jun;285(3):1280-6.
3. Sasaki E, et al. Pharmacology. 2001 Jul;63(1):17-27.
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