Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : TASP0382088
Catalog No.: PC-61455Not For Human Use, Lab Use Only.
A potent, selective ALK5 inhibitor with IC50 of 4.8 nM, >100-fold selectivity over 95 different kinases.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
TASP0382088 is a potent, selective ALK5 inhibitor with IC50 of 4.8 nM, >100-fold selectivity over 95 different kinases.
TASP0382088 inhibits TGF-β-induced Smad2/3 phosphorylation at cellular level with IC50 of 17 nM.
TASP0382088 inhibits Smad2 phosphorylation in mouse skin after topical application.
| M.Wt | 328.408 | |
| Formula | C15H12N4OS2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Amada H, et al. Chem Pharm Bull (Tokyo). 2013;61(3):286-91.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
