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TAT-PDHPS1

Chemical Structure : TAT-PDHPS1

CAS No.:

TAT-PDHPS1

Catalog No.: PC-49185Not For Human Use, Lab Use Only.

TAT-PDHPS1 is an endogenous stable peptide that inhibits the proliferation of ovarian cancer cells in vitro, regulates ovarian cancer development through targeting YAP1 signaling, binds to and interacts with protein phosphatase 2 phosphatase activator (PTPA).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TAT-PDHPS1 is an endogenous stable peptide that inhibits the proliferation of ovarian cancer cells in vitro, regulates ovarian cancer development through targeting YAP1 signaling, binds to and interacts with protein phosphatase 2 phosphatase activator (PTPA).
TAT-PDHPS1 has no obvious adverse effects on ovarian epithelium and hepatorenal function.
TAT-PDHPS1 (10 mmol/L/kg, i.p.) inhibits ovarian tumor growth in xenograft tumors models.

Physicochemical Properties

M.Wt
Formula
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

GRKKRRQRRRPPQQIATTTASAATAAAIGATPRAK

References

1. Xinxing Pan, et al. Mol Cancer Ther. 2022 Jul 5;21(7):1160-1170.

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