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Chemical Structure : TBA-354
CAS No.: 1257426-19-9
Catalog No.: PC-43057Not For Human Use, Lab Use Only.
TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | Get quote |
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TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.
TBA-354 maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates, demonstrates superior potency and pharmacokinetic profile compared with PA-824, 5 to 10 times more potent than PA-824.
| M.Wt | 436.3414 | |
| Formula | C19H15F3N4O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 46 mg/mL |
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| Chemical Name/SMILES |
5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[6-[4-(trifluoromethoxy)phenyl]-3-pyridinyl]methoxy]-, (6S)- |
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1. Kmentova I, et al. J Med Chem. 2010 Dec 9;53(23):8421-39.
2. Upton AM, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):136-44.
3. Tasneen R, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):129-35.
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