TBID |CAS:1639895-85-4 Probechem Biochemicals

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Chemical Structure : TBID

CAS No.: 1639895-85-4

TBID (tBID)

Catalog No.: PC-42167Not For Human Use, Lab Use Only.

tBID is a potent, selective and cell permeable homeodomain-interacting protein kinase 2 (HIPK2) inhibitor with IC50 of 0.33 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

tBID is a potent, selective and cell permeable homeodomain-interacting protein kinase 2 (HIPK2) inhibitor with IC50 of 0.33 uM.
tBID displays selectivity Gini coefficient 0.592 out of a panel of 76 kinases, and also inhibits HIPK1 and HIPK3 with less efficiently.
tBID the first pharmacological tool to down regulate cellular HIPK2 in cells.

Physicochemical Properties

M.Wt	528.7764
Formula	C11H3Br4N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: 26 mg/mL
Chemical Name/SMILES	1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrabromo-2-(1H-imidazol-2-yl)-

References

1. Cozza G, et al. PLoS One. 2014 Feb 24;9(2):e89176.

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TBID (tBID)

Biological Activity

Physicochemical Properties

References

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