TBZE-029 | Enterovirus 2C inhibitor | Probechem Biochemicals

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Chemical Structure : TBZE-029

TBZE-029 (TBZE029)

Catalog No.: PC-62925Not For Human Use, Lab Use Only.

TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication, targets nonstructural protein 2C.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication, targets nonstructural protein 2C.

Physicochemical Properties

M.Wt	356.314
Formula	C16H9F5N2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2,6-difluorophenyl)-6-trifluoromethyl-1H,3H-thiazolo[3,4-a]benzimidazole

References

1. De Palma AM, et al. J Virol. 2008 May;82(10):4720-30.

2. De Palma AM, et al. Biochem Biophys Res Commun. 2007 Feb 16;353(3):628-32.

3. Aguado L, et al. J Med Chem. 2010 Jan 14;53(1):316-24.

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TBZE-029 (TBZE029)

Biological Activity

Physicochemical Properties

References

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