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TBZE-029

Chemical Structure : TBZE-029

CAS No.: 246148-68-5

TBZE-029 (TBZE029)

Catalog No.: PC-62925Not For Human Use, Lab Use Only.

TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication, targets nonstructural protein 2C.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication, targets nonstructural protein 2C.

    Physicochemical Properties

    M.Wt 356.314
    Formula C16H9F5N2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(2,6-difluorophenyl)-6-trifluoromethyl-1H,3H-thiazolo[3,4-a]benzimidazole

    References

    1. De Palma AM, et al. J Virol. 2008 May;82(10):4720-30.

    2. De Palma AM, et al. Biochem Biophys Res Commun. 2007 Feb 16;353(3):628-32.

    3. Aguado L, et al. J Med Chem. 2010 Jan 14;53(1):316-24.

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