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Chemical Structure : TC-DAPK6
CAS No.: 315694-89-4
Catalog No.: PC-22727Not For Human Use, Lab Use Only.
TC-DAPK6 is a potent, specific, ATP-competitiveinhibitor of death associated protein kinase (DAPK) with IC50 of 69 and 225 nM for DAPK1 and ZIPK (DAPK3) respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $128 | In stock | |
| 50 mg | $178 | In stock | |
| 100 mg | Get quote | ||
| 250 mg | Get quote |
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TC-DAPK6 is a potent, specific, ATP-competitiveinhibitor of death associated protein kinase (DAPK) with IC50 of 69 and 225 nM for DAPK1 and ZIPK (DAPK3) respectively.
TC-DAPK6 displays selectivity for DAPK1 over a range of 48 other kinases, including Abl, AMPK, Chk1, Met and Src (IC50 > 10 μM).
| M.Wt | 276.30 | |
| Formula | C17H12N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-(Pyridin-3-ylmethylene)-2-((E)-styryl)oxazol-5(4H)-one |
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1. Zeng W, et al. Acta Biochim Biophys Sin (Shanghai). 2021 Apr 15;53(5):567-574.
2. Okamoto M, et al. J Med Chem. 2009. PMID: 19877644
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