Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-Bacterial-TCA1
TCA1

Chemical Structure : TCA1

CAS No.: 864941-32-2

TCA1 (DprE1/MoeW inhibitor TCA1)

Catalog No.: PC-70348Not For Human Use, Lab Use Only.

TCA1 is a small molecule with activity against drug-resistant and persistent tuberculosis, inhibits DprE1 and MoeW, enzymes involved in cell wall and molybdenum cofactor biosynthesis.

Packing Price Stock Quantity
5 mg $78 In stock
10 mg $118 In stock
25 mg $198 In stock
50 mg $328 In stock
100 mg Get quote

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TCA1 is a small molecule with activity against drug-resistant and persistent tuberculosis, inhibits DprE1 and MoeW, enzymes involved in cell wall and molybdenum cofactor biosynthesis.
TCA1 shows bactericidal activity against nonreplicating Mtb in vitro and is efficacious in acute and chronic Mtb infection mouse models.
TCA1 down-regulates genes known to be involved in Mtb persistence.

Physicochemical Properties

M.Wt 375.417
Formula C16H13N3O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

ethyl (2-(benzo[d]thiazole-2-carboxamido)thiophene-3-carbonyl)carbamate

References

1. Wang F, et al. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2510-7.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: