TCN213 | GluN2A antagonist | Probechem Biochemicals

Chemical Structure : TCN213

CAS No.: 556803-08-8

TCN213 (TCN-213)

Catalog No.: PC-22449Not For Human Use, Lab Use Only.

TCN213 is a selective, glycine-dependently GluN2A-containing NMDARs antagonist with IC50 of 0.55 uM for GluN1/GluN2A NMDAR, negligible effect on GluN1/GluN2B NMDA receptor.

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10 mg	$98	In stock
25 mg	$158	In stock
50 mg	$248	In stock
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Biological Activity

TCN213 is a selective, glycine-dependently GluN2A-containing NMDARs antagonist with IC50 of 0.55 uM for GluN1/GluN2A NMDAR, negligible effect on GluN1/GluN2B NMDA receptor.

Physicochemical Properties

M.Wt	376.54
Formula	C18H24N4OS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((5-(Benzylamino)-1,3,4-thiadiazol-2-yl)thio)-N-(cyclohexylmethyl)acetamide

References

1. McKay S, et al. Br J Pharmacol. 2012 Jun;166(3):924-37.

2. Edman S, et al. Neuropharmacology. 2012 Sep;63(3):441-9.

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TCN213 (TCN-213)

Biological Activity

Physicochemical Properties

References

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