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Chemical Structure : TCP2 inhibitor 163
Catalog No.: PC-20288Not For Human Use, Lab Use Only.
TCP2 inhibitor 163 is a potent, selective inhibitor of tyrosyl-DNA-phosphodiesterases 1 with EC50 of 40 nM in NPPP assays, shows selectivity against TDP1 and APE-1.
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TCP2 inhibitor 163 is a potent, selective inhibitor of tyrosyl-DNA-phosphodiesterases 2 (TDP2) with EC50 of 40 nM in NPPP assays, shows selectivity against TDP1 and APE-1.
| M.Wt | 382.34 | |
| Formula | C19H10N8O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Raoof A, et al. J Med Chem. 2013 Aug 22;56(16):6352-70.
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