TDO inhibitor BNTD

Chemical Structure : TDO inhibitor BNTD

Catalog No.: PC-49658Not For Human Use, Lab Use Only.

BNTD is a highly potent, selective tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50 of 30 nM, > 21-fold selectivity over IDO.

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Biological Activity

BNTD is a highly potent, selective tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50 of 30 nM, > 21-fold selectivity over IDO.

M.Wt	415.45
Formula	C23H21N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(3-(4-methylpiperazine-1-carbonyl)benzyl)-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione

1. Jian-Sung Wu, et al. J Med Chem. 2015 Oct 8;58(19):7807-19.