Catalog No.: PC-20409Not For Human Use, Lab Use Only.
TEAD activator Q2 (Quinolinol Q2) is a small molecule activator of TEAD with EC50 of 2.6 uM in TEAD dual-luciferase reporter (DLR) assays, inhibits TEAD-palmitate interaction with IC50 of 1.7 uM.
TEAD activator Q2 (Quinolinol Q2) is a small molecule activator of TEAD with EC50 of 2.6 uM in TEAD dual-luciferase reporter (DLR) assays, inhibits TEAD-palmitate interaction with IC50 of 1.7 uM.
Quinolinol Q2 directly binds to TEAD with SPR Kd of 2.6 uM, significantly enhances the expression levels of YAP/TAZ-TEAD target genes.
Quinolinol Q2 accelerates cutaneous wound healing in mice, activates nuclear YAP and enhances cell proliferation within days 4-5 postwounding.
