TEAD inhibitor 6

Chemical Structure : TEAD inhibitor 6

Catalog No.: PC-20405Not For Human Use, Lab Use Only.

TEAD inhibitor 6 is a highly potent TEAD inhibitor, disrupts the YAP-TEAD interaction with IC50 of 2.7 nM, binds the main interaction site of YAP at the surface of TEAD.

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Biological Activity

TEAD inhibitor 6 is a highly potent TEAD inhibitor, disrupts the YAP-TEAD interaction with IC50 of 2.7 nM, binds the main interaction site of YAP at the surface of TEAD.

Physicochemical Properties

M.Wt	470.93
Formula	C25H24ClFN2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2S)-2-(aminomethyl)-5-chloro-2-phenyl-2,3-dihydrobenzofuran-4-yl)-3-fluoro-4-(2-methoxyethoxy)benzamide

References

1. Pascal Furet, et al. ChemMedChem. 2022 Oct 6;17(19):e202200303.

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TEAD inhibitor 6

Biological Activity

Physicochemical Properties

References

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