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Chemical Structure : TGN1412
CAS No.:
Catalog No.: PC-Ab1030Not For Human Use, Lab Use Only.
TGN1412 is a novel superagonist anti-CD28 monoclonal antibody that directly stimulates T cells. TGN1412 binds to the laterally exposed C′D loop of CD28 and demonstrated its therapeutic potential for use in autoimmune disease, led to a massive and uncontrolled release of proinflammatory cytokines (cytokine storm) during clinical phase I trials..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $358 | In stock | |
| 5 mg | $758 | In stock | |
| 10 mg | $1280 | In stock | |
| 100 mg | Get quote |
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TGN1412 is a novel superagonist anti-CD28 monoclonal antibody that directly stimulates T cells. TGN1412 binds to the laterally exposed C′D loop of CD28 and demonstrated its therapeutic potential for use in autoimmune disease, led to a massive and uncontrolled release of proinflammatory cytokines (cytokine storm) during clinical phase I trials.
| M.Wt | ||
| Formula | Human IgG4P-Kappa | |
| Appearance | Solid | |
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| Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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