Chemical Structure : TGP-377/421
CAS No.: 16752-89-9
Catalog No.: PC-72390Not For Human Use, Lab Use Only.
TGP-377/421 (Targapre-miR-377/421) is a smalll molecule targets pre-miR-377 and inhibits its processing, binds to miR-377's Dicer processing site with Kd of 29 uM.
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TGP-377/421 (Targapre-miR-377/421) is a smalll molecule targets pre-miR-377 and inhibits its processing, binds to miR-377's Dicer processing site with Kd of 29 uM.
TGP-377/421 inhibits the cellular biogenesis of miR-377 in HUVECs, reduced mature miR-377 levels in a dose-dependent fashion with IC50 of 5 uM, also inhibits miR-421.
M.Wt | 340.39 | |
Formula | C20H16N6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-(3-(6-amino-1H-benzo[d]imidazol-2-yl)phenyl)-1H-benzo[d]imidazol-5-amine |
1. Hafeez S Haniff, et al. Nat Chem. 2020 Oct;12(10):952-961.
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