TH152

Chemical Structure : TH152

Catalog No.: PC-24604Not For Human Use, Lab Use Only.

TH152 is a potent reversible pan-LC3/GABARAP ligand with KD of 2 µM for LC3A in ITC assays, binds all Atg8 family proteins with comparable affinity.

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Biological Activity

TH152 is a potent reversible pan-LC3/GABARAP ligand with KD of 2 µM for LC3A in ITC assays, binds all Atg8 family proteins with comparable affinity.

M.Wt	507.02
Formula	C22H23ClN4O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzoic acid, 4-[2-[[2-[(1-carboxyheptyl)thio]-6-chloro-4-pyrimidinyl]amino]-4-thiazolyl]-

1. Martin P Schwalm, et al. Nat Commun. 2024 Nov 25;15(1):10204.

2. Hanke, T. et al. Bioorg Med Chem Lett24, 3757–3763 (2014).