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Chemical Structure : TH1834
CAS No.: 2108830-08-4
Catalog No.: PC-60498Not For Human Use, Lab Use Only.
TH1834 (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $138 | In stock | |
| 10 mg | $218 | In stock | |
| 25 mg | $368 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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TH1834 (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor; induces apoptosis in breast cancer cell lines with more cytotoxicity than staurosporine.
TH1834 increases the γH2AX foci in the cancer cell lines PC-3 and DU-145 combined with IR.
TH1834 induces apoptosis and increases unrepaired DNA damage in breast cancer cells.
| M.Wt | 568.722 | |
| Formula | C33H40N6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-(5-(4-((phenethyl(4-(4-(pyrrolidin-1-ylmethyl)phenoxy)butyl)amino)methyl)phenyl)-2H-tetrazol-2-yl)acetic acid |
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1. Gao C, et al. Sci Rep. 2014 Jun 20;4:5372.
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