TH1834 dihydrochloride (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor.
TH1834 induces apoptosis in breast cancer cell lines with more cytotoxicity than staurosporine.
TH1834 increases the γH2AX foci in the cancer cell lines PC-3 and DU-145 combined with IR.
TH1834 induces apoptosis and increases unrepaired DNA damage in breast cancer cells.
