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TKIM

Chemical Structure : TKIM

CAS No.: 326921-25-9

TKIM

Catalog No.: PC-24598Not For Human Use, Lab Use Only.

TKIM is a small molecule TREK-1 channel inhibitor with an IC50 of 2.96 μM, binds to the pocket of the intermediate (IM) state of TREK-1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TKIM is a small molecule TREK-1 channel inhibitor with an IC50 of 2.96 μM, binds to the pocket of the intermediate (IM) state of TREK-1.

Physicochemical Properties

M.Wt 371.84
Formula C18H14ClN3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Chloro-N'-(2-(quinolin-2-ylthio)acetyl)benzohydrazide

References

1. Yuqin Ma, et al. J Med Chem. 2020 Oct 8;63(19):10972-10983.

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