Chemical Structure : TKIM
CAS No.: 326921-25-9
Catalog No.: PC-24598Not For Human Use, Lab Use Only.
TKIM is a small molecule TREK-1 channel inhibitor with an IC50 of 2.96 μM, binds to the pocket of the intermediate (IM) state of TREK-1.
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TKIM is a small molecule TREK-1 channel inhibitor with an IC50 of 2.96 μM, binds to the pocket of the intermediate (IM) state of TREK-1.
| M.Wt | 371.84 | |
| Formula | C18H14ClN3O2S | |
| Appearance | Solid | |
| Storage | 
                            
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| Solubility | 
                             10 mM in DMSO  | 
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| Chemical Name/SMILES | 
                             4-Chloro-N'-(2-(quinolin-2-ylthio)acetyl)benzohydrazide  | 
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1. Yuqin Ma, et al. J Med Chem. 2020 Oct 8;63(19):10972-10983.

                
                
                
                
                
                
                
                
            
            
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