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TKN1

Chemical Structure : TKN1

CAS No.: 432533-28-3

TKN1 (TREK channel inhibitor)

Catalog No.: PC-60944Not For Human Use, Lab Use Only.

TKN1 is a small molecule allosteric inhibitor of TREK channels with IC50 of 6.5, 4.4 and 15.7 uM for TREK-1, TREK-2 and TRAAK, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    TKN1 is a small molecule allosteric inhibitor of TREK channels with IC50 of 6.5, 4.4 and 15.7 uM for TREK-1, TREK-2 and TRAAK, respectively.

    Physicochemical Properties

    M.Wt 285.343
    Formula C17H19NO3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(2-hydroxy-5-isopropylphenyl)-2-methoxybenzamide

    References

    1. Luo Q, et al. Nat Commun. 2017 Aug 29;8(1):378.

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