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TKN2

Chemical Structure : TKN2

CAS No.: 886636-57-3

TKN2 (TREK channel inhibitor)

Catalog No.: PC-60945Not For Human Use, Lab Use Only.

TKN2 is a small molecule allosteric inhibitor of TREK channels with IC50 of 3.8, 1.7 and 10.3 uM for TREK-1, TREK-2 and TRAAK, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    TKN2 is a small molecule allosteric inhibitor of TREK channels with IC50 of 3.8, 1.7 and 10.3 uM for TREK-1, TREK-2 and TRAAK, respectively.

    Physicochemical Properties

    M.Wt 350.392
    Formula C19H14N2O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(3-(benzo[d]oxazol-2-yl)-4-hydroxy-5-methylphenyl)thiophene-2-carboxamide

    References

    1. Luo Q, et al. Nat Commun. 2017 Aug 29;8(1):378.

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