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Chemical Structure : TL13-12
Catalog No.: PC-35151Not For Human Use, Lab Use Only.
TL13-12 is a novel Anaplastic Lymphoma Kinase (ALK)-PROTAC developed through conjugation of TAE684 and the cereblon ligand pomalidomide.
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TL13-12 is a novel Anaplastic Lymphoma Kinase (ALK)-PROTAC developed through conjugation of TAE684 and the cereblon ligand pomalidomide.
TL13-12 also promotes the degradation of additional kinases including PTK2 (FAK), Aurora A, FER, and RPS6KA1 (RSK1).
| M.Wt | 961.489 | |
| Formula | C45H53ClN10O10S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Powell CE, et al. J Med Chem. 2018 May 10;61(9):4249-4255.
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