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TM5007

Chemical Structure : TM5007

CAS No.: 342595-05-5

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TM5007 (TM 5007, TM-5007)

Catalog No.: PC-35131Not For Human Use, Lab Use Only.

TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 29 uM, exhibits no inhibitory activity against any of the closely related serpins or serine proteases at 250 uM.

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10 mg $188 In stock
25 mg $328 In stock
50 mg $558 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 29 uM, exhibits no inhibitory activity against any of the closely related serpins or serine proteases at 250 uM.

Physicochemical Properties

M.Wt 560.672
Formula C24H20N2O6S4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5',5'''-(adipoylbis(azanediyl))bis(([2,3'-bithiophene]-4'-carboxylic acid))

References

1. Izuhara Y, et al. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):672-7.

2. Izuhara Y, et al. J Cereb Blood Flow Metab. 2010 May;30(5):904-12.

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