Chemical Structure : TMP269
CAS No.:
1314890-29-3
TMP269
(TMP-269, TMP 269)
Catalog No. : PC-45462Not For Human Use, Lab Use Only.
TMP269 (TMP 269) is a potent and selective class IIa HDAC inhibitor with IC50s of 126/80/36/19 nM for HDAC4/5/7/9.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4546201
Biological Activity
TMP269 (TMP 269) is a potent and selective class IIa HDAC inhibitor with IC50s of 126/80/36/19 nM for HDAC4/5/7/9.
Physicochemical Properties
M.Wt
514.5195
Formula
C25H21F3N4O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 41 mg/mL
Chemical Name/SMILES
Benzamide, N-[[tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-
References
1. Lobera M, et al. Nat Chem Biol.
2. Sinnett-Smith J, et al. Am J Physiol Cell Physiol.
3. Kikuchi S, et al. Leukemia.
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