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TMX-4100

Chemical Structure : TMX-4100

CAS No.: 2367619-63-2

TMX-4100 (TMX4100)

Catalog No.: PC-20153Not For Human Use, Lab Use Only.

TMX-4100 (TMX4100) is a highly potent PDE6D degrader with DC50 of <200 nM in MOLT4 cells, does not degrade CK1α and IKZF1/IKZF3.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TMX-4100 (TMX4100) is a highly potent PDE6D degrader with DC50 of <200 nM in MOLT4 cells, does not degrade CK1α and IKZF1/IKZF3.

Physicochemical Properties

M.Wt 262.29
Formula C11H10N4O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[4-(3-Thienyl)-1H-1,2,3-triazol-1-yl]-2,6-piperidinedione

References

1. Mingxing Teng, et al. J Med Chem. 2022 Jan 13;65(1):747-756.

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