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TMX-4113

Chemical Structure : TMX-4113

CAS No.: 2766385-92-4

TMX-4113 (TMX4113)

Catalog No.: PC-20152Not For Human Use, Lab Use Only.

TMX-4113 (TMX4113) is a highly potent PDE6D degrader with DC50 of 40 nM in MM.1S cells, does not degrade CK1α, IKZF1/IKZF3.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TMX-4113 (TMX4113) is a highly potent PDE6D degrader with DC50 of 40 nM in MM.1S cells, does not degrade CK1α, IKZF1/IKZF3.

Physicochemical Properties

M.Wt 308.37
Formula C12H12N4O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(4-(4-(methylthio)thiophen-3-yl)-1H-1,2,3-triazol-1-yl)piperidine-2,6-dione

References

1. Mingxing Teng, et al. J Med Chem. 2022 Jan 13;65(1):747-756.

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