TMX-4113 | PDE6D PROTAC | Probechem Biochemicals

Chemical Structure : TMX-4113

Catalog No.: PC-20152Not For Human Use, Lab Use Only.

TMX-4113 (TMX4113) is a highly potent PDE6D degrader with DC50 of 40 nM in MM.1S cells, does not degrade CK1α, IKZF1/IKZF3.

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Biological Activity

TMX-4113 (TMX4113) is a highly potent PDE6D degrader with DC50 of 40 nM in MM.1S cells, does not degrade CK1α, IKZF1/IKZF3.

M.Wt	308.37
Formula	C12H12N4O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-(4-(methylthio)thiophen-3-yl)-1H-1,2,3-triazol-1-yl)piperidine-2,6-dione

1. Mingxing Teng, et al. J Med Chem. 2022 Jan 13;65(1):747-756.